Monday, August 30, 2010

Conflicting data

There is not much data on ADT (androgen deprivation therapy. What there is illustrates different response levels dependant on the total picture of the afflicted patient.

For example...disease progression slows in those who are not hormone refractory. At the same time, cardiac issues climb, osteoporosis and diabetes as well. So while mortality from cancer may decrease or longevity increase, the patient dies from cardiac symptoms, hip fractures, or out of control sugar.

Miller's family all have diabetes, except for him. Miller has no elevated cholesterol prior to this treatment. But he has it now. That is being addressed with a statin medication. Increased fractures due to osteoporosis have been shown is studies. That can be (but so far has not been) dealt with using boniva or other medications that encourage bone development.

Thus opting for one treatment over the other as best...can be problematic

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